Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-7-18
pubmed:abstractText
This study was carried out in order to investigate the relationship between endogenous sex steroid hormones and coronary artery disease (CAD). Three hundred and thirty-seven men undergoing coronary angiography were enrolled in the study. Total testosterone, estradiol, free testosterone levels in men with CAD (n = 213) were compared to those of men without CAD (n = 124). No significant differences were found in the serum concentrations of estradiol, total and free testosterone and serum lipid profile between the two groups. Total and free testosterone were negatively (p < 0.05 to p < 0.001) and estradiol was positively (p < 0.05) correlated with age in both groups. Total cholesterol and low-density-lipoprotein levels were positively correlated with the level of free testosterone (r = 0.221, p < 0.01; r = 0.173, p < 0.05, respectively), and high-density-lipoprotein levels were negatively correlated with total testosterone in patients with CAD (r = -0.166, p < 0.05). The results of this study do not support the role of sex steroid hormones in CAD. However, the relationship between sex steroids and serum lipids needs further clarification.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0008-6312
pubmed:author
pubmed:issnType
Print
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-5
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:10844380-Adult, pubmed-meshheading:10844380-Age Distribution, pubmed-meshheading:10844380-Aged, pubmed-meshheading:10844380-Biological Markers, pubmed-meshheading:10844380-Coronary Angiography, pubmed-meshheading:10844380-Coronary Artery Disease, pubmed-meshheading:10844380-Estradiol, pubmed-meshheading:10844380-Humans, pubmed-meshheading:10844380-Incidence, pubmed-meshheading:10844380-Lipoproteins, pubmed-meshheading:10844380-Lipoproteins, HDL, pubmed-meshheading:10844380-Lipoproteins, LDL, pubmed-meshheading:10844380-Male, pubmed-meshheading:10844380-Middle Aged, pubmed-meshheading:10844380-Probability, pubmed-meshheading:10844380-Radioimmunoassay, pubmed-meshheading:10844380-Reference Values, pubmed-meshheading:10844380-Risk Factors, pubmed-meshheading:10844380-Testosterone, pubmed-meshheading:10844380-Triglycerides
pubmed:year
1999
pubmed:articleTitle
Relationship between endogenous sex hormone levels, lipoproteins and coronary atherosclerosis in men undergoing coronary angiography.
pubmed:affiliation
Hacettepe University, Department of Cardiology, Ankara, Turkey. ayliny@ato.org.tr
pubmed:publicationType
Journal Article, Clinical Trial, Controlled Clinical Trial