| pubmed-article:10844106 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10844106 | lifeskim:mentions | umls-concept:C0007226 | lld:lifeskim |
| pubmed-article:10844106 | lifeskim:mentions | umls-concept:C0036866 | lld:lifeskim |
| pubmed-article:10844106 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:10844106 | lifeskim:mentions | umls-concept:C0521329 | lld:lifeskim |
| pubmed-article:10844106 | lifeskim:mentions | umls-concept:C0027358 | lld:lifeskim |
| pubmed-article:10844106 | lifeskim:mentions | umls-concept:C1523909 | lld:lifeskim |
| pubmed-article:10844106 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10844106 | pubmed:dateCreated | 2000-8-29 | lld:pubmed |
| pubmed-article:10844106 | pubmed:abstractText | Putative gender differences in opiate cardiovascular effects were evaluated in spinal rats. After a 4-h exposure to a single dose of morphine (30 mg/kg, i.v.), abstinence was precipitated by naloxone (0.03-3 mg/kg, i.v.). Morphine produced a long-lasting bradycardia and a transient increase in arterial pressure that was similar in both genders. Thereafter, blood pressure decreased both in males and females. Naloxone precipitated a similar dose-dependent heart rate increase in both sexes and a gender-dependent increase in blood pressure. This sex difference appeared in the shape of the response. Prazosin (0.2 mg/kg), prior to naloxone, reduced the pressor response in all animals, suggesting a similar participation of the noradrenergic system in both genders. The present results extend to acute dependence the notion of a sex-dependent differential effect of morphine. The need to consider gender as a factor when studying the effects of opioids is highlighted. | lld:pubmed |
| pubmed-article:10844106 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10844106 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10844106 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10844106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10844106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10844106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10844106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10844106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10844106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10844106 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10844106 | pubmed:month | May | lld:pubmed |
| pubmed-article:10844106 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:10844106 | pubmed:author | pubmed-author:Rodríguez-Man... | lld:pubmed |
| pubmed-article:10844106 | pubmed:author | pubmed-author:CruzS LSL | lld:pubmed |
| pubmed-article:10844106 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10844106 | pubmed:day | 26 | lld:pubmed |
| pubmed-article:10844106 | pubmed:volume | 397 | lld:pubmed |
| pubmed-article:10844106 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10844106 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10844106 | pubmed:pagination | 121-8 | lld:pubmed |
| pubmed-article:10844106 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10844106 | pubmed:meshHeading | pubmed-meshheading:10844106... | lld:pubmed |
| pubmed-article:10844106 | pubmed:meshHeading | pubmed-meshheading:10844106... | lld:pubmed |
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| pubmed-article:10844106 | pubmed:meshHeading | pubmed-meshheading:10844106... | lld:pubmed |
| pubmed-article:10844106 | pubmed:meshHeading | pubmed-meshheading:10844106... | lld:pubmed |
| pubmed-article:10844106 | pubmed:meshHeading | pubmed-meshheading:10844106... | lld:pubmed |
| pubmed-article:10844106 | pubmed:meshHeading | pubmed-meshheading:10844106... | lld:pubmed |
| pubmed-article:10844106 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10844106 | pubmed:articleTitle | Gender differences in the cardiovascular responses to morphine and naloxone in spinal rats. | lld:pubmed |
| pubmed-article:10844106 | pubmed:affiliation | Departamento de Farmacología y Toxicología, Cinvestav, IPN, Apartado Postal 22026, 14000, D.F., Mexico City, Mexico. jcmolcruz@compuserve.com.mx | lld:pubmed |
| pubmed-article:10844106 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10844106 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
