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rdf:type |
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lifeskim:mentions |
umls-concept:C0002932,
umls-concept:C0075804,
umls-concept:C0086418,
umls-concept:C0373746,
umls-concept:C0439799,
umls-concept:C1325742,
umls-concept:C1442488,
umls-concept:C1456384,
umls-concept:C1514562,
umls-concept:C1515877,
umls-concept:C1879547,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221,
umls-concept:C1963547
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|
pubmed:issue |
6
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pubmed:dateCreated |
2000-7-11
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pubmed:abstractText |
Previous studies have identified a volatile anesthetic-induced increase in baseline potassium permeability and concomitant neuronal inhibition. The emerging family of tandem pore domain potassium channels seems to function as baseline potassium channels in vivo. Therefore, we studied the effects of clinically used volatile anesthetics on a recently described member of this family.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0003-3022
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1722-30
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10839924-Anesthetics, Inhalation,
pubmed-meshheading:10839924-Animals,
pubmed-meshheading:10839924-Blotting, Northern,
pubmed-meshheading:10839924-Cloning, Molecular,
pubmed-meshheading:10839924-Humans,
pubmed-meshheading:10839924-Male,
pubmed-meshheading:10839924-Membrane Potentials,
pubmed-meshheading:10839924-Mutagenesis, Site-Directed,
pubmed-meshheading:10839924-Oocytes,
pubmed-meshheading:10839924-Patch-Clamp Techniques,
pubmed-meshheading:10839924-Peripheral Nervous System,
pubmed-meshheading:10839924-Potassium Channels,
pubmed-meshheading:10839924-Potassium Channels, Tandem Pore Domain,
pubmed-meshheading:10839924-Rats,
pubmed-meshheading:10839924-Rats, Sprague-Dawley,
pubmed-meshheading:10839924-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10839924-Spinal Cord,
pubmed-meshheading:10839924-Tissue Distribution,
pubmed-meshheading:10839924-Xenopus laevis
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pubmed:year |
2000
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pubmed:articleTitle |
Volatile anesthetics activate the human tandem pore domain baseline K+ channel KCNK5.
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pubmed:affiliation |
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
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