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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2000-6-14
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pubmed:abstractText |
Brain edema formation following intracerebral hemorrhage (ICH) appears to be partly related to erythrocyte lysis and hemoglobin release. Erythrocyte lysis may be mediated by the complement cascade, which then triggers parenchymal injury. In this study the authors examine whether the complement cascade is activated after ICH and whether inhibition of complement attenuates brain edema around the hematoma.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-3085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1016-22
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10839264-Animals,
pubmed-meshheading:10839264-Brain Diseases,
pubmed-meshheading:10839264-Brain Edema,
pubmed-meshheading:10839264-Cerebral Hemorrhage,
pubmed-meshheading:10839264-Clusterin,
pubmed-meshheading:10839264-Complement Activation,
pubmed-meshheading:10839264-Complement C3d,
pubmed-meshheading:10839264-Complement C9,
pubmed-meshheading:10839264-Glycoproteins,
pubmed-meshheading:10839264-Hematoma,
pubmed-meshheading:10839264-Heparin,
pubmed-meshheading:10839264-Male,
pubmed-meshheading:10839264-Molecular Chaperones,
pubmed-meshheading:10839264-Rats,
pubmed-meshheading:10839264-Rats, Sprague-Dawley,
pubmed-meshheading:10839264-Up-Regulation
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pubmed:year |
2000
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pubmed:articleTitle |
Complement activation in the brain after experimental intracerebral hemorrhage.
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pubmed:affiliation |
Department of Surgery (Neurosurgery), University of Michigan, Ann Arbor 48109-0532, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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