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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2000-8-2
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pubmed:abstractText |
In the fruit fly Drosophila melanogaster, locomotor activity is sexually dimorphic: female flies constantly modulate their activity pattern whereas males show a steadier, stereotyped walking pace [1]. Here, we mapped the area of the brain controlling this behavioural dimorphism. Adult male Drosophila expressing a dominant feminising transgene in a small cluster of neurons in the pars intercerebralis exhibited a female-like pattern of locomotor activity. Genetic ablation of these neurons prevented the feminisation of the locomotor activity of transgenic males. The results suggest that this cluster of neurons modulates sex-specific activity, but is not involved in initiating fly locomotion. Nor does it control male courtship behaviour, because feminisation of courtship was not correlated with the feminisation of locomotor activity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-9822
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
667-70
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10837249-Animals,
pubmed-meshheading:10837249-Animals, Genetically Modified,
pubmed-meshheading:10837249-DNA-Binding Proteins,
pubmed-meshheading:10837249-Drosophila melanogaster,
pubmed-meshheading:10837249-Female,
pubmed-meshheading:10837249-Fungal Proteins,
pubmed-meshheading:10837249-Locomotion,
pubmed-meshheading:10837249-Male,
pubmed-meshheading:10837249-Motor Activity,
pubmed-meshheading:10837249-Nervous System Physiological Phenomena,
pubmed-meshheading:10837249-Neurons,
pubmed-meshheading:10837249-Nuclear Proteins,
pubmed-meshheading:10837249-Recombinant Fusion Proteins,
pubmed-meshheading:10837249-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:10837249-Sex Characteristics,
pubmed-meshheading:10837249-Sexual Behavior, Animal,
pubmed-meshheading:10837249-Transcription Factors
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pubmed:year |
2000
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pubmed:articleTitle |
Genetic identification of neurons controlling a sexually dimorphic behaviour.
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pubmed:affiliation |
UMR-8620, Bases Neurales du Mouvement chez la Drosophile, Université Paris-Sud, Orsay, F-91405, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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