Source:http://linkedlifedata.com/resource/pubmed/id/10834511
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2000-6-14
|
pubmed:abstractText |
We describe a 17-year-old patient with a documented history of Crohn's disease (CD) and of minimal-change nephrotic syndrome (MCNS) in whom a diagnosis of T-cell acute lymphoblastic leukemia (ALL) was made. The diagnosis of ALL was established by morphological examination of bone-marrow aspirates and confirmed by means of immunophenotypic analysis showing the involvement of T-cell lineage leukemic cells. The lymphoid clone showed a karyotypic abnormality involving the long arm of chromosome 5 in a translocation (5;6). Few cases of CD complicated by ALL have been previously reported. The present one is the first case combining CD and ALL in a patient with a past history of MCNS. This raises the possibility of a relationship among those diseases. The possible mechanisms for such a relationship are discussed here.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0939-5555
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
79
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
222-5
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10834511-Adolescent,
pubmed-meshheading:10834511-Chromosome Aberrations,
pubmed-meshheading:10834511-Chromosome Banding,
pubmed-meshheading:10834511-Chromosomes, Human, Pair 5,
pubmed-meshheading:10834511-Crohn Disease,
pubmed-meshheading:10834511-Humans,
pubmed-meshheading:10834511-Immunophenotyping,
pubmed-meshheading:10834511-Karyotyping,
pubmed-meshheading:10834511-Leukemia-Lymphoma, Adult T-Cell,
pubmed-meshheading:10834511-Male,
pubmed-meshheading:10834511-Nephrosis, Lipoid
|
pubmed:year |
2000
|
pubmed:articleTitle |
T-cell lineage acute lymphoblastic leukemia with chromosome 5 abnormality in a patient with Crohn's disease and lipoid nephrosis.
|
pubmed:affiliation |
Service d'Anesthesie et de Réanimation, Hôpital Edouard Herriot, Lyon, France.
|
pubmed:publicationType |
Journal Article,
Case Reports
|