|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001962,
umls-concept:C0023951,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0076823,
umls-concept:C0205145,
umls-concept:C0205251,
umls-concept:C0392762,
umls-concept:C0558295,
umls-concept:C1167622,
umls-concept:C1548147,
umls-concept:C1548328,
umls-concept:C1553412,
umls-concept:C1659436,
umls-concept:C1704650,
umls-concept:C2603343
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pubmed:issue |
5
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|
pubmed:dateCreated |
2000-9-11
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|
pubmed:abstractText |
The locus coeruleus (LC) is the largest norepinephrinergic cell group in the central nervous system and contains a high density of norepinephrine (NE) uptake sites. Alcohol-preferring (AP) rats and high-alcohol-drinking (HAD) rats are selectively bred for high alcohol preference, whereas alcohol-nonpreferring (NP) rats and low-alcohol-drinking (LAD) rats are bred for low alcohol preference. However, it is unknown whether NE uptake sites in the LC are associated with alcohol preference in AP and HAD rats when compared with their respective control rats, NP and LAD rats. This study was designed to examine this question.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0145-6008
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
24
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
588-94
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
|
|
pubmed:year |
2000
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pubmed:articleTitle |
Norepinephrine uptake sites in the locus coeruleus of rat lines selectively bred for high and low alcohol preference: a quantitative autoradiographic binding study using [3H]-tomoxetine.
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|
pubmed:affiliation |
Department of Anatomy, School of Medicine, Indiana University, Indianapolis 46202, USA. hwang@anatomy.iupui.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
