Linked Life Data

10830286

Source:http://linkedlifedata.com/resource/pubmed/id/10830286

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-6-15
pubmed:abstractText
Cell death is a common feature during spermatogenesis and, in some seasonal breeding animals, is often observed at the transition stage from spermatogonia to spermatocytes. In the Japanese red-bellied newt, we have previously shown that this cell death is caused by the elevated titer of plasma PRL that occurs after animals are transferred to low temperature, suggesting that cell death causes the cessation of spermatocytogenesis from late autumn to early spring. In the present report, first we show that the injection of PRL into newts causes apoptosis in spermatogonia after the sixth mitotic division, the penultimate one before spermatogonia normally enter meiosis. Second, we demonstrate in organ cultures of testes fragments that PRL acts directly on the testes. Third, we show that the action by PRL is inhibited by FSH dose dependently.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
141
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2027-32
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Prolactin induces apoptosis in the penultimate spermatogonial stage of the testes in Japanese red-bellied newt (Cynops pyrrhogaster).
pubmed:affiliation
Department of Materials and Life Science, Graduate School of Science and Technology, Kumamoto University, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't