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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1976-6-2
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pubmed:abstractText |
The results reported in this paper suggest that the specific Z-binding cells of the normal mouse include a large portion of T lymphocytes. Depletion of T cells with anti-theta serum and cortisone indicates that the majority of the ZBC of the thymus, which occur at frequencies of about 150/10(6), are indeed T cells. Similar treatment of spleen cells suggests that approximately half the binding cells in that organ are contributed by the T lymphocyte population. T-and B-enriched populations obtained from the spleen by using differential adherence to nylon wool contained equal numbers of ZBC and bound equivalent amounts of the antigen. Hence, there appears to be a high frequency of T lymphocytes that can be shown to bind beta-galactosidase specifically in both the thymus and spleen of normal mice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0022-1767
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
923-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1082908-Animals,
pubmed-meshheading:1082908-Antilymphocyte Serum,
pubmed-meshheading:1082908-B-Lymphocytes,
pubmed-meshheading:1082908-Cell Separation,
pubmed-meshheading:1082908-Cortisone,
pubmed-meshheading:1082908-Galactosidases,
pubmed-meshheading:1082908-Mice,
pubmed-meshheading:1082908-Spleen,
pubmed-meshheading:1082908-T-Lymphocytes,
pubmed-meshheading:1082908-Thymus Gland
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pubmed:year |
1976
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pubmed:articleTitle |
Characterization of T and B antigen-binding cells for beta-galactosidase. II. T antigen-binding cells.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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