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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2000-7-6
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pubmed:abstractText |
To determine the maximum-tolerated dose (MTD) and the dose-limiting toxicities (DLTs) of the raltitrexed plus oxaliplatin combination regimen, to explore its safety and pharmacokinetics, and to assess its antitumor activity in patients with advanced solid tumors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0732-183X
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pubmed:author |
pubmed-author:ArmandJ PJP,
pubmed-author:BonnayMM,
pubmed-author:DanielCC,
pubmed-author:DucreuxMM,
pubmed-author:FandiAA,
pubmed-author:FizaziKK,
pubmed-author:HillCC,
pubmed-author:PoterreMM,
pubmed-author:RuffiéPP,
pubmed-author:SmithMM,
pubmed-author:SoriaJ CJC
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2293-300
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10829050-Adult,
pubmed-meshheading:10829050-Aged,
pubmed-meshheading:10829050-Antimetabolites, Antineoplastic,
pubmed-meshheading:10829050-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:10829050-Area Under Curve,
pubmed-meshheading:10829050-Dose-Response Relationship, Drug,
pubmed-meshheading:10829050-Female,
pubmed-meshheading:10829050-Humans,
pubmed-meshheading:10829050-Male,
pubmed-meshheading:10829050-Middle Aged,
pubmed-meshheading:10829050-Neoplasms,
pubmed-meshheading:10829050-Organoplatinum Compounds,
pubmed-meshheading:10829050-Quinazolines,
pubmed-meshheading:10829050-Thiophenes,
pubmed-meshheading:10829050-Treatment Outcome
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pubmed:year |
2000
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pubmed:articleTitle |
Phase I, dose-finding, and pharmacokinetic study of raltitrexed combined with oxaliplatin in patients with advanced cancer.
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pubmed:affiliation |
Institut Gustave-Roussy, Villejuif, and AstraZeneca Pharmaceuticals, Cergy, France. fizazi@igr.fr
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I
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