Source:http://linkedlifedata.com/resource/pubmed/id/10828412
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2000-8-29
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pubmed:abstractText |
Deficient ability to take advantage of predictable elements in the performance of cognitive tasks has been proposed as an underlying factor for a number of deviances in schizophrenia. In a schizophrenic sample (n=39), we propose and test the view that certain memory and motor anomalies arise because of a compromise in the capacity to take advantage of the redundant (predictable) features of cognitive tasks. Results demonstrate a relationship between reduced capacity to take advantage of predictable features of two different cognitive processing tasks, one verbal memory, and the other motor. Poorer verbal recall on high-redundancy word lists was associated with a reduced ability to produce synchronous finger tapping in response to a high redundancy auditory stimulus, and inversely correlated with formal thought disorder ratings. These relationships, we suggest, reflect a specific and common schizophrenic deficit in the use of redundancies, not attributable to a generalized deficiency in performance. Structural imaging evidence from a subsample of these subjects (n=16) implicates frontal areas as the locus of this cognitive impairment.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0920-9964
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-32
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:10828412-Adult,
pubmed-meshheading:10828412-Attention,
pubmed-meshheading:10828412-Brain Mapping,
pubmed-meshheading:10828412-Cerebral Cortex,
pubmed-meshheading:10828412-Female,
pubmed-meshheading:10828412-Frontal Lobe,
pubmed-meshheading:10828412-Humans,
pubmed-meshheading:10828412-Magnetic Resonance Imaging,
pubmed-meshheading:10828412-Male,
pubmed-meshheading:10828412-Mental Recall,
pubmed-meshheading:10828412-Middle Aged,
pubmed-meshheading:10828412-Neuropsychological Tests,
pubmed-meshheading:10828412-Psychiatric Status Rating Scales,
pubmed-meshheading:10828412-Psychomotor Disorders,
pubmed-meshheading:10828412-Schizophrenia,
pubmed-meshheading:10828412-Schizophrenic Psychology,
pubmed-meshheading:10828412-Verbal Learning
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pubmed:year |
2000
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pubmed:articleTitle |
Impaired verbal memory is associated with impaired motor performance in schizophrenia: relationship to brain structure.
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pubmed:affiliation |
Department of Psychiatry, Dr. John C. Corrigan Mental Health Center, 49 Hillside Street, 02720, Fall River, MA 02215, USA. theo.manschreck@dmh.state.ma.us
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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