Source:http://linkedlifedata.com/resource/pubmed/id/10824201
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2000-8-9
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pubmed:abstractText |
To evaluate the role of phaseolinone, a phytotoxin produced by Macrophomina phaseolina, in disease initiation, three nontoxigenic avirulent mutants of the fungus were generated by UV-mutagenesis. Two of them were able to initiate infection in germinating Phaseolus mungo seeds only in the presence of phaseolinone. The minimum dose of phaseoli-none required for infection in 30% seedlings was 2 5 mg/ml. A human pathogen, Aspergillus fumigatus was also able to infect germinating seeds of P. mungo in the presence of 5 mg/ml concentration of phaseolinone. Phaseolinone seemed to facilitate infection by A. fumigatus, which is not normally phytopathogenic, by reducing the immunity of germinating seedlings in a nonspecific way. Levamisole, a non-specific immunopotentiator gave protection against infection induced by A. fumigatus at an optimum dose of 50 mg/ml. Sodium malonate prevented the effects of levamisole.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adjuvants, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Levamisole,
http://linkedlifedata.com/resource/pubmed/chemical/Mycotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Naphthols,
http://linkedlifedata.com/resource/pubmed/chemical/phaseolinone
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0250-5991
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
73-80
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10824201-Adjuvants, Immunologic,
pubmed-meshheading:10824201-Aspergillus fumigatus,
pubmed-meshheading:10824201-Drug Interactions,
pubmed-meshheading:10824201-Fabaceae,
pubmed-meshheading:10824201-Immunity, Innate,
pubmed-meshheading:10824201-Levamisole,
pubmed-meshheading:10824201-Mitosporic Fungi,
pubmed-meshheading:10824201-Mutation,
pubmed-meshheading:10824201-Mycotoxins,
pubmed-meshheading:10824201-Naphthols,
pubmed-meshheading:10824201-Plant Diseases,
pubmed-meshheading:10824201-Plants, Medicinal,
pubmed-meshheading:10824201-Seeds
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pubmed:year |
2000
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pubmed:articleTitle |
Avirulent mutants of Macrophomina phaseolina and Aspergillus fumigatus initiate infection in Phaseolus mungo in the presence of phaseolinone; levamisole gives protection.
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pubmed:affiliation |
Indian Institute of Chemical Biology, 4, Raja S C Mullick Road, Jadavpur, Calcutta 700 032, India.
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pubmed:publicationType |
Journal Article
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