pubmed-article:10822353 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0037047 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0240069 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0170657 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0023745 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0034987 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C0599883 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
pubmed-article:10822353 | lifeskim:mentions | umls-concept:C1709450 | lld:lifeskim |
pubmed-article:10822353 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:10822353 | pubmed:dateCreated | 2000-8-3 | lld:pubmed |
pubmed-article:10822353 | pubmed:abstractText | A functional polymorphism in the regulatory region of the serotonin transporter gene (5-HTTLPR) has been reported to be both associated and linked to anxiety-related personality measures, although other studies have not replicated these findings. The current study examines both association and linkage of the gene to two major anxiety-related personality measures, the harm avoidance scale on the Tridimensional Personality Questionnaire and the neuroticism scale of the NEO-PI-R, in a sample of 148 Israeli subjects comprising 74 same-sex sibling pairs. We replicated the reported association between the short allele and higher scores on the TPQ harm avoidance scale (P = 0.03), including the subscale of shyness (P = 0.02), and also found association in the same direction between the short allele and the NEO-PI-R neuroticism subscales of anxiety (P = 0.03) and depression (P = 0.04). Sib-pair linkage analysis, using the regression method, further supported a role of the 5-HTTLPR in anxiety-related personality traits. | lld:pubmed |
pubmed-article:10822353 | pubmed:language | eng | lld:pubmed |
pubmed-article:10822353 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10822353 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:10822353 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10822353 | pubmed:month | Mar | lld:pubmed |
pubmed-article:10822353 | pubmed:issn | 1359-4184 | lld:pubmed |
pubmed-article:10822353 | pubmed:author | pubmed-author:BenjaminJJ | lld:pubmed |
pubmed-article:10822353 | pubmed:author | pubmed-author:HamerDD | lld:pubmed |
pubmed-article:10822353 | pubmed:author | pubmed-author:OsherYY | lld:pubmed |
pubmed-article:10822353 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10822353 | pubmed:volume | 5 | lld:pubmed |
pubmed-article:10822353 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10822353 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10822353 | pubmed:pagination | 216-9 | lld:pubmed |
pubmed-article:10822353 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:10822353 | pubmed:year | 2000 | lld:pubmed |
pubmed-article:10822353 | pubmed:articleTitle | Association and linkage of anxiety-related traits with a functional polymorphism of the serotonin transporter gene regulatory region in Israeli sibling pairs. | lld:pubmed |
pubmed-article:10822353 | pubmed:affiliation | Beer Sheva Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, POB 4600, Beer Sheva, Israel. | lld:pubmed |
pubmed-article:10822353 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:10822353 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
pubmed-article:10822353 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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