Source:http://linkedlifedata.com/resource/pubmed/id/10817905
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-10-18
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pubmed:abstractText |
In the chicken, arginine vasotocin (AVT) is produced in and secreted by magnocellular neurons in the supraoptic (SON) and paraventricular (PVN) nuclei. To test the hypothesis of axonally transported AVT mRNA, the localization of AVT mRNA within extrasomal, axonal/dendritic compartments in the chicken hypothalamo-neurohypophysial system (HNS) were examined using AVT specific in situ hybridization histochemistry (ISHH) and RT-PCR. Many perikarya in the PVN and external--but none in the ventral subgroup of the SON show ISHH signals clearly extended into one or two processes, some with branching collaterals, traceable over a distance of more than 100 microns. Furthermore by using RT-PCR, AVT mRNA was detected in the median eminence and neurohypophysis representing the distal parts of the HNS, mainly consisting of axons and/or axon terminals. These observations of axonal mRNA offer new insights to the organization and function of the avian HNS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1096-4959
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
189-95
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10817905-Animals,
pubmed-meshheading:10817905-Axons,
pubmed-meshheading:10817905-Blotting, Southern,
pubmed-meshheading:10817905-Brain Chemistry,
pubmed-meshheading:10817905-Chickens,
pubmed-meshheading:10817905-Female,
pubmed-meshheading:10817905-Histocytochemistry,
pubmed-meshheading:10817905-Hypothalamo-Hypophyseal System,
pubmed-meshheading:10817905-In Situ Hybridization,
pubmed-meshheading:10817905-Male,
pubmed-meshheading:10817905-Neurons,
pubmed-meshheading:10817905-Paraventricular Hypothalamic Nucleus,
pubmed-meshheading:10817905-Presynaptic Terminals,
pubmed-meshheading:10817905-RNA, Messenger,
pubmed-meshheading:10817905-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10817905-Supraoptic Nucleus,
pubmed-meshheading:10817905-Vasotocin
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pubmed:year |
2000
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pubmed:articleTitle |
Localization of arginine vasotocin (AVT) mRNA in extrasomal compartments of magnocellular neurons in the chicken hypothalamo-neurohypophysial system.
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pubmed:affiliation |
Department of Physiology, Federal Research Centre of Agriculture (FAL), Celle, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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