Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2000-10-18
pubmed:abstractText
In the chicken, arginine vasotocin (AVT) is produced in and secreted by magnocellular neurons in the supraoptic (SON) and paraventricular (PVN) nuclei. To test the hypothesis of axonally transported AVT mRNA, the localization of AVT mRNA within extrasomal, axonal/dendritic compartments in the chicken hypothalamo-neurohypophysial system (HNS) were examined using AVT specific in situ hybridization histochemistry (ISHH) and RT-PCR. Many perikarya in the PVN and external--but none in the ventral subgroup of the SON show ISHH signals clearly extended into one or two processes, some with branching collaterals, traceable over a distance of more than 100 microns. Furthermore by using RT-PCR, AVT mRNA was detected in the median eminence and neurohypophysis representing the distal parts of the HNS, mainly consisting of axons and/or axon terminals. These observations of axonal mRNA offer new insights to the organization and function of the avian HNS.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1096-4959
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-95
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Localization of arginine vasotocin (AVT) mRNA in extrasomal compartments of magnocellular neurons in the chicken hypothalamo-neurohypophysial system.
pubmed:affiliation
Department of Physiology, Federal Research Centre of Agriculture (FAL), Celle, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't