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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2000-7-11
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pubmed:databankReference |
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pubmed:abstractText |
A new SHV-derived extended-spectrum beta-lactamase (SHV-24) conferring high-level resistance to ceftazidime but not cefotaxime and cefazolin was identified in Japan. This enzyme was encoded by a transferable 150-kb plasmid from an Escherichia coli clinical isolate. The pI and K(m) for CAZ of this enzyme were 7.5 and 30 microM, respectively. SHV-24 was found to have a D179G substitution in the Omega-loop of the enzyme.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-10231522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-10689165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-2039479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-2653216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-8141584,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-8619581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-8793392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-8834878,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-9044020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-9056008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-9228783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-9231421,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-9420027,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-9675457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10817740-9925786
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0066-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1725-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
2000
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pubmed:articleTitle |
A new SHV-derived extended-spectrum beta-lactamase (SHV-24) that hydrolyzes ceftazidime through a single-amino-acid substitution (D179G) in the -loop.
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pubmed:affiliation |
Department of Bacterial and Blood Products, National Institute of Infectious Diseases, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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