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| pubmed-article:10817689 | lifeskim:mentions | umls-concept:C0033105 | lld:lifeskim |
| pubmed-article:10817689 | lifeskim:mentions | umls-concept:C0370215 | lld:lifeskim |
| pubmed-article:10817689 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:10817689 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:10817689 | lifeskim:mentions | umls-concept:C0039260 | lld:lifeskim |
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| pubmed-article:10817689 | lifeskim:mentions | umls-concept:C1710133 | lld:lifeskim |
| pubmed-article:10817689 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:10817689 | pubmed:dateCreated | 2000-7-11 | lld:pubmed |
| pubmed-article:10817689 | pubmed:abstractText | Twenty (8.5%) of 234 nonrepetitive clinical isolates of Klebsiella pneumoniae from southern Taiwan were found to produce extended-spectrum beta-lactamases (ESBLs): 10 strains produced SHV-12, 4 produced SHV-5, 2 produced a non-TEM non-SHV ESBL with a pI of 8.3, 3 produced a novel AmpC beta-lactamase designated CMY-8 with a pI of 8.25, and 1 produced SHV-12 and an unidentified AmpC enzyme with a pI of 8.2. The CMY-8 enzyme confers a resistance phenotype similar to CMY-1 and MOX-1, and sequence comparisons showed high homologies (>95%) of nucleotide and amino acid sequences among these three enzymes. Plasmid and pulse-field gel electrophoresis analyses revealed that all isolates harboring an SHV-derived ESBL were genetically unrelated, indicating that dissemination of resistance plasmids is responsible for the spread of SHV ESBLs among K. pneumoniae in this area. All three isolates carrying CMY-8 had identical genotypic patterns, suggesting the presence of an epidemic strain. | lld:pubmed |
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| pubmed-article:10817689 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10817689 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10817689 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:10817689 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10817689 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:10817689 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:10817689 | pubmed:author | pubmed-author:YaoJ KJK | lld:pubmed |
| pubmed-article:10817689 | pubmed:author | pubmed-author:SuI JIJ | lld:pubmed |
| pubmed-article:10817689 | pubmed:author | pubmed-author:WuS MSM | lld:pubmed |
| pubmed-article:10817689 | pubmed:author | pubmed-author:TsaiS HSH | lld:pubmed |
| pubmed-article:10817689 | pubmed:author | pubmed-author:WuJ JJJ | lld:pubmed |
| pubmed-article:10817689 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10817689 | pubmed:volume | 44 | lld:pubmed |
| pubmed-article:10817689 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10817689 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10817689 | pubmed:pagination | 1438-42 | lld:pubmed |
| pubmed-article:10817689 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:10817689 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10817689 | pubmed:articleTitle | Prevalence of SHV-12 among clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamases and identification of a novel AmpC enzyme (CMY-8) in Southern Taiwan. | lld:pubmed |
| pubmed-article:10817689 | pubmed:affiliation | Department of Pathology, National Cheng Kung University Medical Center, Tainan, Taiwan. | lld:pubmed |
| pubmed-article:10817689 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10817689 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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