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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2000-6-7
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pubmed:abstractText |
Acute wound healing has been extensively investigated over the years, however, little is known about possible healing defects in chronic wounds. Fibronectin (FN) plays a critical role in different phases of wound healing and has been demonstrated to be degraded in chronic wounds by proteases. Fibroblasts cultured from chronic leg ulcers showed a higher level of FN compared to normal fibroblasts.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1076-0512
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
447-51
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10816233-Acute Disease,
pubmed-meshheading:10816233-Adult,
pubmed-meshheading:10816233-Aged,
pubmed-meshheading:10816233-Aged, 80 and over,
pubmed-meshheading:10816233-Case-Control Studies,
pubmed-meshheading:10816233-Chronic Disease,
pubmed-meshheading:10816233-DNA Probes,
pubmed-meshheading:10816233-Female,
pubmed-meshheading:10816233-Fibronectins,
pubmed-meshheading:10816233-Humans,
pubmed-meshheading:10816233-Immunohistochemistry,
pubmed-meshheading:10816233-In Situ Hybridization,
pubmed-meshheading:10816233-Leg Ulcer,
pubmed-meshheading:10816233-Male,
pubmed-meshheading:10816233-Middle Aged,
pubmed-meshheading:10816233-Mohs Surgery,
pubmed-meshheading:10816233-RNA, Messenger,
pubmed-meshheading:10816233-Receptors, Fibronectin,
pubmed-meshheading:10816233-Skin,
pubmed-meshheading:10816233-Up-Regulation,
pubmed-meshheading:10816233-Wound Healing
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pubmed:year |
2000
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pubmed:articleTitle |
Level of fibronectin mRNA is markedly increased in human chronic wounds.
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pubmed:affiliation |
Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
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pubmed:publicationType |
Journal Article
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