Source:http://linkedlifedata.com/resource/pubmed/id/10816198
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2000-6-13
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pubmed:abstractText |
We conducted a retrospective, 7 year cohort survey to examine the natural changes in peritoneal equilibration test (PET) results in patients with long-term uneventful continuous ambulatory peritoneal dialysis (CAPD). Thirty-two (17 males, 15 females) patients on CAPD with two or more standard PETs performed more than 6 months apart, in the absence of peritoneal insult, were included. Changes and pattern of PET results were evaluated by the dialysate to plasma ratio of creatinine (D:P-cre), the fourth h dialysate to instilled glucose ratio (D4:Do) and ultrafiltration volume (UF, ml). The subgroups included high (H), high-average (HA), low-average (LA), or low (L) transporters with the dividing ratios (D:P-cre) of >0.81, >0. 65 to 0.81, >0.5 to 0.65, and <0.5, respectively. The median D:P-cre significantly decreased (p = 0.04), but neither the D4:Do nor the final median UF significantly decreased. The change in D:P-cre was strongly and inversely correlated with the initial D:P-cre value (r = -0.68; p < 0.05). A similar relationship was found between the change in the final D4:Do and the initial D4:Do (r = -0.752; p < 0. 01) and between the change in the final UF and the initial UF (r = -0.875; p < 0.01). No correlation was found between the change in D:P-cre and the age of the patient, the time interval between PETs, monthly dialysate glucose exposure, or underlying diabetes/non-diabetes. The final peritoneal transport pattern was altered with 5 (15.6%) patients remaining in the extreme subgroups (H or L) and, by contrast, 84.4% (27/32) of the patients now in the averaged (HA or LA) groups (p < 0.01, chi2 test). We demonstrated a natural "centralization" migration of PET results after long-term uneventful CAPD, which may help to explain why patients with extreme PET characteristics, that is, H or L, continued to do well on CAPD.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0160-564X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10816198-Adult,
pubmed-meshheading:10816198-Age Factors,
pubmed-meshheading:10816198-Chi-Square Distribution,
pubmed-meshheading:10816198-Cohort Studies,
pubmed-meshheading:10816198-Creatinine,
pubmed-meshheading:10816198-Diabetes Complications,
pubmed-meshheading:10816198-Dialysis Solutions,
pubmed-meshheading:10816198-Female,
pubmed-meshheading:10816198-Glucose,
pubmed-meshheading:10816198-Humans,
pubmed-meshheading:10816198-Kidney Diseases,
pubmed-meshheading:10816198-Kidney Glomerulus,
pubmed-meshheading:10816198-Linear Models,
pubmed-meshheading:10816198-Longitudinal Studies,
pubmed-meshheading:10816198-Male,
pubmed-meshheading:10816198-Peritoneal Dialysis, Continuous Ambulatory,
pubmed-meshheading:10816198-Peritoneum,
pubmed-meshheading:10816198-Retrospective Studies,
pubmed-meshheading:10816198-Risk Factors,
pubmed-meshheading:10816198-Time Factors,
pubmed-meshheading:10816198-Ultrafiltration
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pubmed:year |
2000
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pubmed:articleTitle |
Natural changes in peritoneal equilibration test results in continuous ambulatory peritoneal dialysis patients: a retrospective, seven year cohort survey.
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pubmed:affiliation |
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
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pubmed:publicationType |
Journal Article
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