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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-6-13
pubmed:abstractText
We conducted a retrospective, 7 year cohort survey to examine the natural changes in peritoneal equilibration test (PET) results in patients with long-term uneventful continuous ambulatory peritoneal dialysis (CAPD). Thirty-two (17 males, 15 females) patients on CAPD with two or more standard PETs performed more than 6 months apart, in the absence of peritoneal insult, were included. Changes and pattern of PET results were evaluated by the dialysate to plasma ratio of creatinine (D:P-cre), the fourth h dialysate to instilled glucose ratio (D4:Do) and ultrafiltration volume (UF, ml). The subgroups included high (H), high-average (HA), low-average (LA), or low (L) transporters with the dividing ratios (D:P-cre) of >0.81, >0. 65 to 0.81, >0.5 to 0.65, and <0.5, respectively. The median D:P-cre significantly decreased (p = 0.04), but neither the D4:Do nor the final median UF significantly decreased. The change in D:P-cre was strongly and inversely correlated with the initial D:P-cre value (r = -0.68; p < 0.05). A similar relationship was found between the change in the final D4:Do and the initial D4:Do (r = -0.752; p < 0. 01) and between the change in the final UF and the initial UF (r = -0.875; p < 0.01). No correlation was found between the change in D:P-cre and the age of the patient, the time interval between PETs, monthly dialysate glucose exposure, or underlying diabetes/non-diabetes. The final peritoneal transport pattern was altered with 5 (15.6%) patients remaining in the extreme subgroups (H or L) and, by contrast, 84.4% (27/32) of the patients now in the averaged (HA or LA) groups (p < 0.01, chi2 test). We demonstrated a natural "centralization" migration of PET results after long-term uneventful CAPD, which may help to explain why patients with extreme PET characteristics, that is, H or L, continued to do well on CAPD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0160-564X
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:10816198-Adult, pubmed-meshheading:10816198-Age Factors, pubmed-meshheading:10816198-Chi-Square Distribution, pubmed-meshheading:10816198-Cohort Studies, pubmed-meshheading:10816198-Creatinine, pubmed-meshheading:10816198-Diabetes Complications, pubmed-meshheading:10816198-Dialysis Solutions, pubmed-meshheading:10816198-Female, pubmed-meshheading:10816198-Glucose, pubmed-meshheading:10816198-Humans, pubmed-meshheading:10816198-Kidney Diseases, pubmed-meshheading:10816198-Kidney Glomerulus, pubmed-meshheading:10816198-Linear Models, pubmed-meshheading:10816198-Longitudinal Studies, pubmed-meshheading:10816198-Male, pubmed-meshheading:10816198-Peritoneal Dialysis, Continuous Ambulatory, pubmed-meshheading:10816198-Peritoneum, pubmed-meshheading:10816198-Retrospective Studies, pubmed-meshheading:10816198-Risk Factors, pubmed-meshheading:10816198-Time Factors, pubmed-meshheading:10816198-Ultrafiltration
pubmed:year
2000
pubmed:articleTitle
Natural changes in peritoneal equilibration test results in continuous ambulatory peritoneal dialysis patients: a retrospective, seven year cohort survey.
pubmed:affiliation
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
pubmed:publicationType
Journal Article