Source:http://linkedlifedata.com/resource/pubmed/id/10807979
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2000-7-14
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pubmed:abstractText |
Reference values for serum haptoglobin (Hp), were established in a Black Zimbabwean population. The upper limit (2.15 g/l) is comparable to the one in Caucasians, but the lower limit (0.12 g/l) is much lower than the proposed interim international reference limit (0.3 g/l). Subjects that typed as Hp 0-0 by starch gel electrophoresis technique were retyped using high performance gel permeation chromatography. This resulted in a 32% decrease in the frequency of Hp 0-0, but an increase in Hp 2-2 and Hp 2-1M phenotype frequencies. In the Zimbabwean Blacks, the Hp 0-0 frequency was estimated to be 2.9%. Haptoglobin reference values were found to be Hp phenotype-dependent; highest values were found in Hp 1-1 (median 0.88 g/l; range 0.31-1.69 g/l) and in Hp 2-1 (median 0.90 g/l; range 0.31-2.22 g/l) and lower values (median 0.66 g/l; range 0.13-1.79 g/l) in Hp 2-2 subjects. The Hp 2-1M phenotype was characterized by low reference values (0.18-1.25 g/l) (P<0.05). In three cases of the rare variant Hp Johnson, high Hp concentrations were found (median 1. 57 g/l; range 0.98-1.57 g/l).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0009-8981
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
296
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-70
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10807979-Adult,
pubmed-meshheading:10807979-African Continental Ancestry Group,
pubmed-meshheading:10807979-Aged,
pubmed-meshheading:10807979-Aged, 80 and over,
pubmed-meshheading:10807979-Alleles,
pubmed-meshheading:10807979-Electrophoresis, Starch Gel,
pubmed-meshheading:10807979-Female,
pubmed-meshheading:10807979-Gene Frequency,
pubmed-meshheading:10807979-Haptoglobins,
pubmed-meshheading:10807979-Humans,
pubmed-meshheading:10807979-Male,
pubmed-meshheading:10807979-Middle Aged,
pubmed-meshheading:10807979-Phenotype,
pubmed-meshheading:10807979-Polymorphism, Genetic,
pubmed-meshheading:10807979-Reference Values,
pubmed-meshheading:10807979-Sex Characteristics,
pubmed-meshheading:10807979-Zimbabwe
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pubmed:year |
2000
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pubmed:articleTitle |
Reference range of serum haptoglobin is haptoglobin phenotype-dependent in blacks.
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pubmed:affiliation |
Departments of Medicine and Chemical Pathology, Medical School, The University of Zimbabwe, Harare, Zimbabwe.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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