Linked Life Data

10805997

Source:http://linkedlifedata.com/resource/pubmed/id/10805997

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-6-8
pubmed:abstractText
Cholinesterase (ChE) activity was measured in plasma, whole blood [using 5,5'-dithiobis(2-nitrobenzoic acid) and 2-PDS as chromophores], brain, and whole eyes of Anguilla anguilla exposed to a sublethal concentration of 11.15 mg/L (one-third of the 96-h LC(50)) of the carbamate herbicide molinate. ChE activity was evaluated after 6, 24, 48, 72, and 96 h of pesticide exposure. Results indicated that ChE activity in eel tissues decreased as time of exposure increased, especially in eel blood. Eels exposed to molinate were transferred to a pesticide-free water for a recovery period of 4 days and ChE activity was also evaluated. Results indicated that ChE activity for those animals with preexposure to the carbamate was still different from the controls even after the recovery period. The use of hematological parameters for assessing the toxicity of molinate in A. anguilla was also studied. The parameters included the measurement of blood proteins, hematocrit, hemoglobin, erythrocytes, and leukocytes. Molinate exposure produced a decrease in all the hematological parameters tested, which was significant only during the recovery period. These results indicate that ChE activity, as well as hematological parameters, may be useful as a diagnostic test for molinate exposure in aquatic organisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0147-6513
pubmed:author
pubmed:copyrightInfo
Copyright 2000 Academic Press.
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Cholinesterase activity and hematological parameters as biomarkers of sublethal molinate exposure in Anguilla anguilla.
pubmed:affiliation
Department of Animal Physiology, Faculty of Biological Sciences, University of Valencia, Dr. Moliner 50, Burjassot, Valencia, 46100, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't