Linked Life Data

10804537

Source:http://linkedlifedata.com/resource/pubmed/id/10804537

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2000-6-13
pubmed:abstractText
The detection of fetal intracardiac echogenic foci (ICEF) by ultrasound was first reported in 1987. Despite many investigations, the relationship of ICEF with congenital heart malformations and chromosomal abnormalities remains unclear. This review describes the current understanding of ICEF based on a literature search from 1980 to the present. ICEF are observed in 0.5 to 20 percent of fetuses, with an overall frequency of 5.6 percent. These small, discrete structures near the papillary muscles and chordae tendinae move in synchrony with the intraventricular valves. They likely represent microcalcification of the papillary muscles. ICEF are most commonly seen in the left ventricle and occasionally in the right ventricle or bilaterally. Intra-atrial or diffuse ICEF are rare. In the chromosomally normal fetus, ICEF are not associated with congenital heart defects. The presence of ICEF in fetuses at high risk for chromosomal abnormalities suggests an increased possibility of aneuploidy, especially if other sonographic markers are noted. A similar association is observed with trisomy 21 in particular. The significance of ICEF in fetuses at low risk for aneuploidy is less clear and represents an area for future research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0029-7828
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
303-11
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Fetal intracardiac echogenic foci: current understanding and clinical significance.
pubmed:affiliation
Department of Obstetrics and Gynecology, Hartford Hospital, Connecticut 06102, USA.
pubmed:publicationType
Journal Article, Review