Source:http://linkedlifedata.com/resource/pubmed/id/10804140
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2000-7-19
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pubmed:abstractText |
Episodes of acute gastroenteritis in prospectively followed children between 2 months and 2 years of age were examined for rotaviruses, enteric adenoviruses, astroviruses, and human caliciviruses, including both Norwalk-like viruses (NLVs) and Sapporo-like viruses (SLVs), using PCR and reverse transcription (RT)-PCR assays. A virus was identified in 60% (502/832) of all episodes and in 85% of the moderately severe or severe episodes. Human caliciviruses were as common as rotaviruses, both being detected in 29% of the cases. NLVs accounted for a 20% etiologic share of all cases; the clinical picture was a moderately severe disease with vomiting as a predominant symptom. SLVs were detected in 9% of the cases, the clinical picture being a mild diarrheal disease. Astroviruses were found in 10% and enteric adenoviruses in 6% of the cases. Diagnosis with PCR and RT-PCR methods increases the detection of all gastroenteritis viruses, particularly human caliciviruses. As a group, human caliciviruses are common causative agents of gastroenteritis in children <2 years of age in Finland, and, of these, NLVs cause more severe disease than SLVs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
181 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S288-94
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10804140-Acute Disease,
pubmed-meshheading:10804140-Caliciviridae,
pubmed-meshheading:10804140-Child, Preschool,
pubmed-meshheading:10804140-Double-Blind Method,
pubmed-meshheading:10804140-Feces,
pubmed-meshheading:10804140-Gastroenteritis,
pubmed-meshheading:10804140-Humans,
pubmed-meshheading:10804140-Immunoenzyme Techniques,
pubmed-meshheading:10804140-Infant,
pubmed-meshheading:10804140-Prospective Studies,
pubmed-meshheading:10804140-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10804140-Rotavirus
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pubmed:year |
2000
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pubmed:articleTitle |
Human caliciviruses in acute gastroenteritis of young children in the community.
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pubmed:affiliation |
Department of Virology and Pediatrics, University of Tampere Medical School, Tampere, Finland. llxipa@uta.fi.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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