|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001186,
umls-concept:C0033618,
umls-concept:C0243072,
umls-concept:C0439849,
umls-concept:C0441655,
umls-concept:C0445223,
umls-concept:C1280500,
umls-concept:C1533691,
umls-concept:C1548818,
umls-concept:C1552599,
umls-concept:C1704787
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2000-5-22
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|
pubmed:abstractText |
We set out to measure drug binding to serum proteins. These have been shown to reduce the free plasma concentrations of a number of anticancer drugs, particularly of those of complex organic structure, in both experimental studies and clinical trials.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0344-5704
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
45
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
417-22
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10803926-Amsacrine,
pubmed-meshheading:10803926-Animals,
pubmed-meshheading:10803926-Antineoplastic Agents,
pubmed-meshheading:10803926-Blood Proteins,
pubmed-meshheading:10803926-Carcinoma, Lewis Lung,
pubmed-meshheading:10803926-Cattle,
pubmed-meshheading:10803926-Doxorubicin,
pubmed-meshheading:10803926-Etoposide,
pubmed-meshheading:10803926-Humans,
pubmed-meshheading:10803926-Mice,
pubmed-meshheading:10803926-Mitoxantrone,
pubmed-meshheading:10803926-Orosomucoid,
pubmed-meshheading:10803926-Protein Binding,
pubmed-meshheading:10803926-Serum Albumin,
pubmed-meshheading:10803926-Vincristine
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Effects of protein binding on the in vitro activity of antitumour acridine derivatives and related anticancer drugs.
|
|
pubmed:affiliation |
Auckland Cancer Society Research Centre, University of Auckland School of Medicine, New Zealand. g.finlay@auckland.ac.nz
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
