Source:http://linkedlifedata.com/resource/pubmed/id/10803793
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4 Suppl
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pubmed:dateCreated |
2000-6-29
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pubmed:abstractText |
Although epidemiological studies indicate that ethanol consumption and the risk of breast cancer are positively associated in women, experimental animal models have not yet been developed that provide evidence to support this relationship. To clarify alcohol-related liver injury, it is important to reproduce, in laboratory small animals, the liver fibrosis observed in human alcoholics. However, in mice the induction of fibrosis has failed. The present study describes the first experimental models to produce mammary tumors in female ICR mice and liver fibrosis in male ICR mice treated long-term with ethanol.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0145-6008
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
117S-122S
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:10803793-Animals,
pubmed-meshheading:10803793-Body Weight,
pubmed-meshheading:10803793-Drinking,
pubmed-meshheading:10803793-Ethanol,
pubmed-meshheading:10803793-Female,
pubmed-meshheading:10803793-Liver Cirrhosis, Alcoholic,
pubmed-meshheading:10803793-Male,
pubmed-meshheading:10803793-Mammary Neoplasms, Experimental,
pubmed-meshheading:10803793-Mice,
pubmed-meshheading:10803793-Mice, Inbred ICR
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pubmed:year |
2000
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pubmed:articleTitle |
Long-term ethanol consumption in ICR mice causes mammary tumor in females and liver fibrosis in males.
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pubmed:affiliation |
Department of Legal Medicine, Kansai Medical University, Moriguchi, Japan.
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pubmed:publicationType |
Journal Article
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