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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2000-7-18
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pubmed:abstractText |
Hepatitis C virus (HCV) infection is currently the most common cause of fibrosing liver disease and represents a major clinical challenge. In patients with HCV infection, inflammation and injury lead to fibrosis and cirrhosis in a significant proportion of patients; cirrhosis in turn has multiple clinical sequelae. Therefore, understanding the pathological basis of fibrogenesis in hepatitis C infection is critical. This review will highlight fundamental issues underlying the fibrogenic response to injury and in addition will focus on potential points of intervention.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1049-5118
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
69-83
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10803632-Adrenal Cortex Hormones,
pubmed-meshheading:10803632-Animals,
pubmed-meshheading:10803632-Biopsy,
pubmed-meshheading:10803632-Cells, Cultured,
pubmed-meshheading:10803632-Colchicine,
pubmed-meshheading:10803632-Disease Progression,
pubmed-meshheading:10803632-Drug Therapy, Combination,
pubmed-meshheading:10803632-Female,
pubmed-meshheading:10803632-Hepatitis C, Chronic,
pubmed-meshheading:10803632-Humans,
pubmed-meshheading:10803632-Interferons,
pubmed-meshheading:10803632-Liver,
pubmed-meshheading:10803632-Liver Cirrhosis,
pubmed-meshheading:10803632-Liver Function Tests,
pubmed-meshheading:10803632-Male,
pubmed-meshheading:10803632-Middle Aged,
pubmed-meshheading:10803632-Prognosis,
pubmed-meshheading:10803632-Retinoids
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pubmed:year |
2000
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|
pubmed:articleTitle |
Hepatic fibrogenesis and hepatitis C.
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|
pubmed:affiliation |
Liver Center and Department of Medicine and Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Case Reports
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