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pubmed-article:10803285pubmed:dateCreated2000-5-25lld:pubmed
pubmed-article:10803285pubmed:abstractTextWe have been studying some properties of the new generation photosensitizers--phthalocyanines. The influence of the certain phthalocyanine concentrations at combination with laser irradiation doses (semiconductor laser, lambda = 670 nm, P = 50 mW) have been studied by in vitro fluorescent methods. Cytotoxicity assay LIVE/DEAD for fluorescence microscopy and measurements of cells viability with multi-well plate scanner was used. The optimal phototoxic effect on MCF7--mamma carcinoma cells was observed 8 micrograms/ml ZnPcS2, 10 micrograms/ml ClAlPcS2 in combination with laser irradiation 50 J/cm2 and 100 J/cm2 respectively. This concentration and dose killed MCF7 carcinoma cells.lld:pubmed
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pubmed-article:10803285pubmed:pagination437-42lld:pubmed
pubmed-article:10803285pubmed:dateRevised2009-11-11lld:pubmed
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pubmed-article:10803285pubmed:year1998lld:pubmed
pubmed-article:10803285pubmed:articleTitle[Fluorescence methods for studying cell damage].lld:pubmed
pubmed-article:10803285pubmed:affiliationUstav lékarské biofyziky, Lékarské fakulty, Univerzita Palackého, Olomouc, Czech Republic.lld:pubmed
pubmed-article:10803285pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10803285pubmed:publicationTypeEnglish Abstractlld:pubmed
pubmed-article:10803285pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed