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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-5-25
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pubmed:abstractText |
We have been studying some properties of the new generation photosensitizers--phthalocyanines. The influence of the certain phthalocyanine concentrations at combination with laser irradiation doses (semiconductor laser, lambda = 670 nm, P = 50 mW) have been studied by in vitro fluorescent methods. Cytotoxicity assay LIVE/DEAD for fluorescence microscopy and measurements of cells viability with multi-well plate scanner was used. The optimal phototoxic effect on MCF7--mamma carcinoma cells was observed 8 micrograms/ml ZnPcS2, 10 micrograms/ml ClAlPcS2 in combination with laser irradiation 50 J/cm2 and 100 J/cm2 respectively. This concentration and dose killed MCF7 carcinoma cells.
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pubmed:language |
cze
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0036-5327
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
437-42
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:10803285-Breast Neoplasms,
pubmed-meshheading:10803285-Cell Survival,
pubmed-meshheading:10803285-Female,
pubmed-meshheading:10803285-Fluoresceins,
pubmed-meshheading:10803285-Fluorescent Dyes,
pubmed-meshheading:10803285-Humans,
pubmed-meshheading:10803285-Indoles,
pubmed-meshheading:10803285-Lasers,
pubmed-meshheading:10803285-Microscopy, Fluorescence,
pubmed-meshheading:10803285-Radiation Dosage,
pubmed-meshheading:10803285-Radiation-Sensitizing Agents,
pubmed-meshheading:10803285-Tumor Cells, Cultured
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pubmed:year |
1998
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pubmed:articleTitle |
[Fluorescence methods for studying cell damage].
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pubmed:affiliation |
Ustav lékarské biofyziky, Lékarské fakulty, Univerzita Palackého, Olomouc, Czech Republic.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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