Linked Life Data

10798246

Source:http://linkedlifedata.com/resource/pubmed/id/10798246

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-6-9
pubmed:abstractText
The interaction of 20 antibiotics with the cationic surfactant cetyltrimethylammonium bromide (CTAB) was studied by charge-transfer reversed-phase chromatography carried out on impregnated alumina layers using water-methanol mixtures as eluents. The lipophilicity and specific hydrophobic surface area of antibiotics and the relative strength of their interaction with CTAB was calculated. CTAB interacted with 10 antibiotics the antibiotic--CTAB complex generally being more hydrophilic than the uncomplexed molecule. The relative strength of interaction depended considerably on the molecular structure of the antibiotics. Significant linear correlation was found between the lipophilicity of antibiotics and their capacity to interact with CTAB indicating the involvement of hydrophobic forces in the interaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
303-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Charge-transfer chromatographic study of the interaction of antibiotics with cetyltrimethylammonium bromide.
pubmed:affiliation
Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest, Hungary. forgacs@cric.chemres.hu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't