Source:http://linkedlifedata.com/resource/pubmed/id/10792366
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2000-8-21
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pubmed:abstractText |
The role of Immunoglobulin (Ig)E in inflammation is the subject of considerable study and a number of studies have shown conflicting evidence for its role in eosinophil recruitment and bronchial hyperresponsiveness in a number of murine models. The low affinity IgE receptor, CD23, is known to act as a negative regulator of IgE production and we have used knockout mice deficient in CD23 to investigate the role of IgE in eosinophil recruitment and bronchial hyperresponsiveness in a murine model of airway inflammation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0954-7894
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
728-38
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10792366-Allergens,
pubmed-meshheading:10792366-Animals,
pubmed-meshheading:10792366-Bronchial Hyperreactivity,
pubmed-meshheading:10792366-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:10792366-Immunoglobulin E,
pubmed-meshheading:10792366-Mice,
pubmed-meshheading:10792366-Mice, Inbred C57BL,
pubmed-meshheading:10792366-Mice, Knockout,
pubmed-meshheading:10792366-Pulmonary Eosinophilia,
pubmed-meshheading:10792366-Receptors, IgE,
pubmed-meshheading:10792366-Respiratory Mucosa
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pubmed:year |
2000
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pubmed:articleTitle |
The role of CD23 on allergen-induced IgE levels, pulmonary eosinophilia and bronchial hyperresponsiveness in mice.
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pubmed:affiliation |
The Sackler Institute of Pulmonary Pharmacology, Division of Pharmacology and Therapeutics, GKT School of Biomedical Sciences, King's College London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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