rdf:type |
|
lifeskim:mentions |
umls-concept:C0016360,
umls-concept:C0017262,
umls-concept:C0025663,
umls-concept:C0038952,
umls-concept:C0040085,
umls-concept:C0080103,
umls-concept:C0185117,
umls-concept:C0185125,
umls-concept:C0680730,
umls-concept:C0699790,
umls-concept:C1148554,
umls-concept:C1441616,
umls-concept:C1548787,
umls-concept:C2911684
|
pubmed:issue |
3
|
pubmed:dateCreated |
2000-7-14
|
pubmed:abstractText |
Thymidylate synthase (TS) is regarded as a parameter of 5-fluorouracil (5-FU) chemosensitivity for colorectal carcinoma. Recent researchers indicate that the chemosensitivity of 5-FU for colorectal carcinoma with low expression of TS is better than tumors with high expression of TS. But the relation between TS expression and overall survival of curatively resected colorectal cancer patients has been less studied.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1068-9265
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
193-8
|
pubmed:dateRevised |
2007-7-18
|
pubmed:meshHeading |
pubmed-meshheading:10791849-Antimetabolites, Antineoplastic,
pubmed-meshheading:10791849-Carcinoma,
pubmed-meshheading:10791849-Chi-Square Distribution,
pubmed-meshheading:10791849-Colonic Neoplasms,
pubmed-meshheading:10791849-Female,
pubmed-meshheading:10791849-Fluorouracil,
pubmed-meshheading:10791849-Humans,
pubmed-meshheading:10791849-Immunohistochemistry,
pubmed-meshheading:10791849-Male,
pubmed-meshheading:10791849-Middle Aged,
pubmed-meshheading:10791849-Proportional Hazards Models,
pubmed-meshheading:10791849-Statistics, Nonparametric,
pubmed-meshheading:10791849-Survival Analysis,
pubmed-meshheading:10791849-Thymidylate Synthase,
pubmed-meshheading:10791849-Treatment Outcome
|
pubmed:year |
2000
|
pubmed:articleTitle |
Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method.
|
pubmed:affiliation |
Department of Surgical Oncology, University of Tokyo, Japan. takenoue-1su@h.u-tokyo.ac.jp
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|