rdf:type |
|
lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0017398,
umls-concept:C0017428,
umls-concept:C0162741,
umls-concept:C0205341,
umls-concept:C0242772,
umls-concept:C0330209,
umls-concept:C0683598,
umls-concept:C0699759,
umls-concept:C1148916,
umls-concept:C1334043
|
pubmed:issue |
1
|
pubmed:dateCreated |
2000-7-11
|
pubmed:abstractText |
The presence of a single resistance (R) gene allele can determine plant disease resistance. The protein products of such genes may act as receptors that specifically interact with pathogen-derived factors. Most functionally defined R-genes are of the nucleotide binding site-leucine rich repeat (NBS-LRR) supergene family and are present as large multigene families. The specificity of R-gene interactions together with the robustness of plant-pathogen interactions raises the question of their gene number and diversity in the genome. Genomic sequences from tomato showing significant homology to genes conferring race-specific resistance to pathogens were identified by systematically "scanning" the genome using a variety of primer pairs based on ubiquitous NBS motifs. Over 70 sequences were isolated and 10% are putative pseudogenes. Mapping of the amplified sequences on the tomato genetic map revealed their organization as mixed clusters of R-gene homologues that showed in many cases linkage to genetically characterized tomato resistance loci. Interspecific examination within Lycopersicon showed the existence of a null allele. Consideration of the tomato and potato comparative genetic maps unveiled conserved syntenic positions of R-gene homologues. Phylogenetic clustering of R-gene homologues within tomato and other Solanaceae family members was observed but not with R-gene homologues from Arabidopsis thaliana. Our data indicate remarkably rapid evolution of R-gene homologues during diversification of plant families.
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-10072407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-10214940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-10334979,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-10364408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-10754062,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-1360934,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-17246482,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-17246486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-1980523,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-2515110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7549479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7638602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7756690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7770053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7827490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7902614,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7915554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7923358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7923359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-7973631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8091210,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8100724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8200357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8525370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8552038,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8582620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8608599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8647402,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8664498,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8689679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8876208,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8876209,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8944022,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-8953768,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9012350,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9115193,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9144960,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9144966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9254694,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9352645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9396791,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9418057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9419382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9435236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9437864,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9465073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9482816,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9530866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9634592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9670562,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9675895,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9707531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9707547,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9724691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9811791,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9811793,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9811794,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9811798,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10790405-9847076
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0016-6731
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
155
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
309-22
|
pubmed:dateRevised |
2010-9-14
|
pubmed:meshHeading |
|