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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-6-9
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pubmed:abstractText |
A study of neuropsychological performance was conducted in 33 HIV+ patients initiating highly active antiretroviral therapy (HAART). Grooved Pegboard (GP) non-dominant hand performance improved in 23/33 (70%) subjects (P=0.002). Among 23 patients with motor slowing (GP non-dominant hand z score < -1.0) at baseline, 18 (78%) improved on the GP non-dominant hand test after initiating HAART (P=0.001). GP non-dominant hand performance improved longitudinally in HIV+ patients initiating HAART, while matched HIV+ controls not on HAART did not change (P=0.045). Significant improvement in motor performance can occur after HAART in HIV+ patients with impairment.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1355-0284
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
84-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10787000-AIDS Dementia Complex,
pubmed-meshheading:10787000-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:10787000-Adult,
pubmed-meshheading:10787000-Anti-HIV Agents,
pubmed-meshheading:10787000-Female,
pubmed-meshheading:10787000-Functional Laterality,
pubmed-meshheading:10787000-HIV Protease Inhibitors,
pubmed-meshheading:10787000-HIV Seropositivity,
pubmed-meshheading:10787000-Hand,
pubmed-meshheading:10787000-Humans,
pubmed-meshheading:10787000-Longitudinal Studies,
pubmed-meshheading:10787000-Male,
pubmed-meshheading:10787000-Middle Aged,
pubmed-meshheading:10787000-Movement Disorders,
pubmed-meshheading:10787000-Neuropsychological Tests,
pubmed-meshheading:10787000-Prospective Studies,
pubmed-meshheading:10787000-Psychomotor Performance,
pubmed-meshheading:10787000-Viral Load
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pubmed:year |
2000
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pubmed:articleTitle |
Improvement in HIV-associated motor slowing after antiretroviral therapy including protease inhibitors.
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pubmed:affiliation |
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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