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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2000-6-8
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pubmed:abstractText |
The loss of p53 function is a recognized adverse prognostic factor in invasive breast cancer. Several studies have shown a relationship between the nuclear accumulation of p53 protein (a surrogate marker of p53 inactivation) and poor disease-free and overall survival. In general, however, these studies did not report the prognostic value of p53 for local failure, which we have therefore assessed retrospectively here.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0732-183X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1906-13
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10784631-Adult,
pubmed-meshheading:10784631-Aged,
pubmed-meshheading:10784631-Breast Neoplasms,
pubmed-meshheading:10784631-Disease-Free Survival,
pubmed-meshheading:10784631-Female,
pubmed-meshheading:10784631-Genes, p53,
pubmed-meshheading:10784631-Humans,
pubmed-meshheading:10784631-Immunohistochemistry,
pubmed-meshheading:10784631-Mastectomy, Radical,
pubmed-meshheading:10784631-Middle Aged,
pubmed-meshheading:10784631-Neoplasm Recurrence, Local,
pubmed-meshheading:10784631-Predictive Value of Tests,
pubmed-meshheading:10784631-Prognosis,
pubmed-meshheading:10784631-Retrospective Studies,
pubmed-meshheading:10784631-Tumor Suppressor Protein p53
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pubmed:year |
2000
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pubmed:articleTitle |
Prognostic value of p53 for local failure in mastectomy-treated breast cancer patients.
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pubmed:affiliation |
Department of Radiology (Division of Radiation Oncology), University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7800, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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