Source:http://linkedlifedata.com/resource/pubmed/id/10782671
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
2000-6-20
|
| pubmed:abstractText |
4-Thiazolidinones were synthesized and evaluated for their ability to inhibit the bacterial enzyme MurB. Selected 4-thiazolidinones displayed activity against the enzyme in vitro. This activity, coupled with the design principles of the thiazolidinones, supports the postulate that 4-thiazolidinones may be recognized as diphosphate mimics by a biological selector.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0960-894X
|
| pubmed:author |
pubmed-author:AndresC JCJ,
pubmed-author:BronsonJ JJJ,
pubmed-author:D'AndreaS VSV,
pubmed-author:DeshpandeM SMS,
pubmed-author:DiepB NBN,
pubmed-author:Grant-YoungK AKA,
pubmed-author:HarteW EWE,
pubmed-author:HoH THT,
pubmed-author:MiscoP FPF,
pubmed-author:RobertsonJ GJG,
pubmed-author:StockDD,
pubmed-author:SunYY,
pubmed-author:WalshA WAW
|
| pubmed:issnType |
Print
|
| pubmed:day |
17
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
715-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
2000
|
| pubmed:articleTitle |
4-Thiazolidinones: novel inhibitors of the bacterial enzyme MurB.
|
| pubmed:affiliation |
Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, CT 06492, USA.
|
| pubmed:publicationType |
Journal Article
|