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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-5-25
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pubmed:abstractText |
Because the prostaglandin endoperoxide H synthase-1 (PGHS-1)-dependent formation of thromboxane A(2) is an important modulator of platelet function, this pathway represents a pharmacologic target for the inhibition of platelet function by aspirin. The objective of our research was to study how PGHS-1 expression is regulated in platelets.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Glycoprotein GPIIb-IIIa...,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Glycoprotein GPIb-IX...,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tetradecanoylphorbol Acetate
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0301-472X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
411-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10781899-Cell Adhesion,
pubmed-meshheading:10781899-Cell Differentiation,
pubmed-meshheading:10781899-Cell Division,
pubmed-meshheading:10781899-Cell Line,
pubmed-meshheading:10781899-Cell Survival,
pubmed-meshheading:10781899-Cyclooxygenase 1,
pubmed-meshheading:10781899-Fluorescent Antibody Technique,
pubmed-meshheading:10781899-Humans,
pubmed-meshheading:10781899-Immunohistochemistry,
pubmed-meshheading:10781899-Isoenzymes,
pubmed-meshheading:10781899-Megakaryocytes,
pubmed-meshheading:10781899-Membrane Proteins,
pubmed-meshheading:10781899-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:10781899-Platelet Glycoprotein GPIb-IX Complex,
pubmed-meshheading:10781899-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:10781899-RNA, Messenger,
pubmed-meshheading:10781899-Tetradecanoylphorbol Acetate
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pubmed:year |
2000
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pubmed:articleTitle |
Characterization of prostaglandin endoperoxide H synthase-1 enzyme expression during differentiation of the megakaryocytic cell line MEG-01.
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pubmed:affiliation |
Department of Biochemistry, Microbiology and Immunology, Ottawa, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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