rdf:type |
|
lifeskim:mentions |
umls-concept:C0014327,
umls-concept:C0014442,
umls-concept:C0017262,
umls-concept:C0021853,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0035696,
umls-concept:C0064294,
umls-concept:C0185117,
umls-concept:C0851285,
umls-concept:C2911684
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pubmed:issue |
2
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pubmed:dateCreated |
2000-6-8
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pubmed:abstractText |
Malnutrition is associated with increased reactive oxygen species (ROS) formation and depletion of the critical antioxidant glutathione (GSH) in the intestine. The malnutrition-induced decrease in gut GSH levels is prevented by recombinant keratinocyte growth factor (KGF) administration. We investigated whether enzymes that are induced by oxidants and modulate tissue GSH supply are regulated by enteral nutrients or KGF at the messenger RNA (mRNA) level.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Fgf7 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 10,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 7,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamate-Cysteine Ligase,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione Transferase,
http://linkedlifedata.com/resource/pubmed/chemical/Growth Substances,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/gamma-Glutamyltransferase
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pubmed:status |
MEDLINE
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pubmed:issn |
0148-6071
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
67-75
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10772185-Analysis of Variance,
pubmed-meshheading:10772185-Animals,
pubmed-meshheading:10772185-Enteral Nutrition,
pubmed-meshheading:10772185-Fasting,
pubmed-meshheading:10772185-Fibroblast Growth Factor 10,
pubmed-meshheading:10772185-Fibroblast Growth Factor 7,
pubmed-meshheading:10772185-Fibroblast Growth Factors,
pubmed-meshheading:10772185-Glutamate-Cysteine Ligase,
pubmed-meshheading:10772185-Glutathione,
pubmed-meshheading:10772185-Glutathione Transferase,
pubmed-meshheading:10772185-Growth Substances,
pubmed-meshheading:10772185-In Situ Hybridization,
pubmed-meshheading:10772185-Intestines,
pubmed-meshheading:10772185-Male,
pubmed-meshheading:10772185-RNA, Messenger,
pubmed-meshheading:10772185-Rats,
pubmed-meshheading:10772185-Rats, Sprague-Dawley,
pubmed-meshheading:10772185-gamma-Glutamyltransferase
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pubmed:articleTitle |
Enteral nutrition and keratinocyte growth factor regulate expression of glutathione-related enzyme messenger RNAs in rat intestine.
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pubmed:affiliation |
Department of Medicine, Emory University, Atlanta, Georgia 30322, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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