Source:http://linkedlifedata.com/resource/pubmed/id/10770350
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2000-5-2
|
| pubmed:abstractText |
To investigate the prevalence of the HIV-1 subtypes in different populations from Salvador, Bahia, Brazil, blood samples from 72 HIV-1-seropositive injecting drug users (IDUs) and 62 individuals infected sexually were analyzed using the heteroduplex mobility assay (HMA). In the IDU group, 89.5% were classified as subtype B, 3% as subtype F, and 7.5% showed a B/F HMA profile. In the sexual transmission (ST) group, 95% were identified as B subtype, 3.4% showed a B/F profile, and 1.6% a B/C/E HMA profile. All Brazilian samples that showed multiple reactivities in the HMA analysis clustered on sequencing with B North American/ European HIV-1 isolates in the phylogenetic analysis, whereas the F subtypes clustered with F Brazilian HIV-I isolates. Serologic reactivities of IDU's sera were examined using a panel of synthetic V3 loop peptides representative of the different HIV-1 subtypes. No difference in serologic reactivity between F and B subtype plasma could be observed. Predominance of HIV-I subtype B was identified in both study groups, whereas subtype F was detected only among IDUs in a frequency lower than described for other Brazilian regions.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
1525-4135
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
22
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
288-93
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:10770350-Adolescent,
pubmed-meshheading:10770350-Adult,
pubmed-meshheading:10770350-Africa,
pubmed-meshheading:10770350-African Continental Ancestry Group,
pubmed-meshheading:10770350-Antigenic Variation,
pubmed-meshheading:10770350-Brazil,
pubmed-meshheading:10770350-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10770350-Female,
pubmed-meshheading:10770350-HIV Infections,
pubmed-meshheading:10770350-HIV-1,
pubmed-meshheading:10770350-Heteroduplex Analysis,
pubmed-meshheading:10770350-Humans,
pubmed-meshheading:10770350-Male,
pubmed-meshheading:10770350-Middle Aged,
pubmed-meshheading:10770350-Phylogeny,
pubmed-meshheading:10770350-Polymerase Chain Reaction,
pubmed-meshheading:10770350-Sexual Behavior,
pubmed-meshheading:10770350-Socioeconomic Factors,
pubmed-meshheading:10770350-Substance Abuse, Intravenous
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics.
|
| pubmed:affiliation |
Advanced Laboratory of Public Health-LASP, Gonçalo Moniz Research Center-CPqGM, Oswaldo Cruz Foundation, UNAIDS Collaborating Center, Salvador, Bahia. coutofer@gene.dbbm.fiocruz.br
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|