Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2000-5-12
pubmed:abstractText
Various epidemiological studies suggested that individuals with high intake of antioxidant vitamins (E, A and C) have a better cardiovascular prognosis than subjects with relative deficiencies in such vitamins. However, placebo-controlled randomized clinical trials did not demonstrate that a specific supplementation in either alpha-tocopherol (vitamin E) or beta-carotene (vitamin A) allows to reduce the incidence of major cardiovascular events, in the general population or even in various subgroups at high risk, and there is no such controlled trials with vitamin C alone. Some studies suggested that combined supplements of several antioxidant vitamins might be more efficacious, and these observations led to initiate several large controlled studies. Thus, until now, there is no convincing arguments in the literature in favour of artificial supplements of antioxidant vitamins. It seems preferable to encourage a well-balanced healthy diet while awaiting the results of the large prospective ongoing trials with combined supplementation.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0370-629X
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
[Antioxidant vitamins in the prevention of cardiovascular diseases. 2nd part: results of clinical trials].
pubmed:affiliation
Université de Liège, Département de Médecine.
pubmed:publicationType
Journal Article, English Abstract