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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2000-5-4
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pubmed:abstractText |
In patients with atherosclerosis, hepatic hydroxymethylglutaryl coenzyme A reductase (CSE) inhibitors may reduce the activation of inflammation. Because Chlamydia pneumoniae infection has been linked to coronary artery disease through the induction of plaque inflammation, we investigated whether cerivastatin affects the infection rate of human macrophages and endothelial cells (ECs) and their proinflammatory activation after chlamydial infection.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
18
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1760-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10769273-Adult,
pubmed-meshheading:10769273-Arteriosclerosis,
pubmed-meshheading:10769273-Bronchitis,
pubmed-meshheading:10769273-Cells, Cultured,
pubmed-meshheading:10769273-Chlamydia Infections,
pubmed-meshheading:10769273-Chlamydophila pneumoniae,
pubmed-meshheading:10769273-Chronic Disease,
pubmed-meshheading:10769273-Cytokines,
pubmed-meshheading:10769273-Endothelium, Vascular,
pubmed-meshheading:10769273-Humans,
pubmed-meshheading:10769273-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:10769273-Inflammation,
pubmed-meshheading:10769273-Macrophages, Alveolar,
pubmed-meshheading:10769273-Male,
pubmed-meshheading:10769273-Middle Aged,
pubmed-meshheading:10769273-NF-kappa B,
pubmed-meshheading:10769273-Pyridines,
pubmed-meshheading:10769273-Statistics, Nonparametric,
pubmed-meshheading:10769273-Superoxides
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pubmed:year |
2000
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pubmed:articleTitle |
Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae.
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pubmed:affiliation |
Department of Internal Medicine II, Medical University of Lübeck, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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