|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0021655,
umls-concept:C0031621,
umls-concept:C0086418,
umls-concept:C0205082,
umls-concept:C0205296,
umls-concept:C0205314,
umls-concept:C0205419,
umls-concept:C0221099,
umls-concept:C0679622,
umls-concept:C1150493,
umls-concept:C1418576,
umls-concept:C1418577,
umls-concept:C1423080,
umls-concept:C1423613,
umls-concept:C2003941
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2000-6-6
|
|
pubmed:abstractText |
Phosphoinositide 3-kinase (PI 3K) plays a central part in the mediation of insulin-stimulated glucose disposal. No genetic studies of this enzyme in human syndromes of severe insulin resistance have been previously reported.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0012-186X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
43
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
321-31
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:10768093-Adult,
pubmed-meshheading:10768093-Base Sequence,
pubmed-meshheading:10768093-Cell Line,
pubmed-meshheading:10768093-Fasting,
pubmed-meshheading:10768093-Female,
pubmed-meshheading:10768093-Genetic Variation,
pubmed-meshheading:10768093-Humans,
pubmed-meshheading:10768093-Insulin,
pubmed-meshheading:10768093-Insulin Resistance,
pubmed-meshheading:10768093-Male,
pubmed-meshheading:10768093-Pedigree,
pubmed-meshheading:10768093-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:10768093-Phosphorylation,
pubmed-meshheading:10768093-Polymorphism, Genetic,
pubmed-meshheading:10768093-Signal Transduction,
pubmed-meshheading:10768093-Tyrosine
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity.
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|
pubmed:affiliation |
Department of Medicine, University of Cambridge, UK.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
