Source:http://linkedlifedata.com/resource/pubmed/id/10767365
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-5-16
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pubmed:abstractText |
We studied the Cd44v8-10 expression in gallbladder cancer immunohistochemically. Eighteen of 37 gallbladder cancer tissues expressed CD44v8-10. There were significant correlations between CD44v8-10 immunoreactivity and perineural invasion, venous invasion, and lymph node metastasis. Patients with CD44v8-10-positive tumors showed poor prognoses, whereas those with CD44v8-10-negative tumors had favorable prognoses. A multivariate analysis using the Cox regression model showed the immunoreactivity of CD44v8-10 to be an independent prognostic indicator of gallbladder cancer. The results suggest that CD44v8-10 expression may be a biologic marker of prognostic significance in gallbladder cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1021-335X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
541-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10767365-Antigens, CD,
pubmed-meshheading:10767365-Antigens, CD44,
pubmed-meshheading:10767365-Disease-Free Survival,
pubmed-meshheading:10767365-Gallbladder Neoplasms,
pubmed-meshheading:10767365-Genetic Variation,
pubmed-meshheading:10767365-Humans,
pubmed-meshheading:10767365-Lymphatic Metastasis,
pubmed-meshheading:10767365-Multivariate Analysis,
pubmed-meshheading:10767365-Neoplasm Invasiveness,
pubmed-meshheading:10767365-Neoplasm Metastasis,
pubmed-meshheading:10767365-Neoplasm Staging,
pubmed-meshheading:10767365-Prognosis,
pubmed-meshheading:10767365-Retrospective Studies,
pubmed-meshheading:10767365-Survival Rate,
pubmed-meshheading:10767365-Time Factors
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pubmed:articleTitle |
Expression of variant CD44 containing variant exon v8-10 in gallbladder cancer.
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pubmed:affiliation |
First Department of Surgery, Fukui Medical University, Yoshida-gun, Fukui 910-1193, Japan.
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pubmed:publicationType |
Journal Article
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