Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2000-5-10
pubmed:abstractText
Interleukin-2 (IL-2) and granulocyte-macrophage-colony stimulating factor (GM-CSF) are cytokines with nonoverlapping pleiotropic effects. In a prior Phase Ib study, this combination of agents exhibited antitumor effects in the lungs of four of eight patients with renal cell carcinoma and pulmonary metastases. We conducted this Phase Ib/II trial to determine the response rate of renal cell carcinoma patients with pulmonary metastases treated with continuous infusion IL-2 plus GM-CSF.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0008-543X
pubmed:author
pubmed:copyrightInfo
Copyright 2000 American Cancer Society.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1892-901
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:10760767-Adult, pubmed-meshheading:10760767-Aged, pubmed-meshheading:10760767-Carcinoma, Renal Cell, pubmed-meshheading:10760767-Cerebral Hemorrhage, pubmed-meshheading:10760767-Drug Administration Schedule, pubmed-meshheading:10760767-Drug Therapy, Combination, pubmed-meshheading:10760767-Fatal Outcome, pubmed-meshheading:10760767-Female, pubmed-meshheading:10760767-Granulocyte-Macrophage Colony-Stimulating Factor, pubmed-meshheading:10760767-Humans, pubmed-meshheading:10760767-Interleukin-2, pubmed-meshheading:10760767-Intracranial Thrombosis, pubmed-meshheading:10760767-Kidney Neoplasms, pubmed-meshheading:10760767-Lung Neoplasms, pubmed-meshheading:10760767-Male, pubmed-meshheading:10760767-Middle Aged, pubmed-meshheading:10760767-Nervous System, pubmed-meshheading:10760767-Treatment Outcome, pubmed-meshheading:10760767-Venous Thrombosis
pubmed:year
2000
pubmed:articleTitle
A phase Ib/II trial of granulocyte-macrophage-colony stimulating factor and interleukin-2 for renal cell carcinoma patients with pulmonary metastases: a case of fatal central nervous system thrombosis.
pubmed:affiliation
Department of Medicine, University of Wisconsin, Madison, Wisconsin 53792, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Case Reports, Research Support, Non-U.S. Gov't, Clinical Trial, Phase II, Clinical Trial, Phase I