Source:http://linkedlifedata.com/resource/pubmed/id/10760564
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-3
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| pubmed:dateCreated |
2000-7-6
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| pubmed:abstractText |
One of the early genes in aflatoxin biosynthesis, avnA, encodes a pathway-specific cytochrome P-450 monooxygenase that catalyzes the hydroxylation of the polyketide anthraquinone, averantin. Based on beta-glucuronidase (GUS) reporter and electrophoretic mobility shift assays, promoter sites upstream of -118 bp in the 367-bp verB-avnA intergenic region are not required for avnA gene activity. Therefore, only the -100 to -110 site of the four putative binding sites for AFLR, the aflatoxin biosynthetic pathway transcription regulatory protein (consensus binding sequence: 5'-TCGN(5)CGR-3') was required for elevated avnA expression.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0006-3002
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
25
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| pubmed:volume |
1491
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
7-12
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| pubmed:dateRevised |
2008-11-21
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| pubmed:meshHeading |
pubmed-meshheading:10760564-Aflatoxins,
pubmed-meshheading:10760564-Aspergillus,
pubmed-meshheading:10760564-Base Sequence,
pubmed-meshheading:10760564-Gene Expression Regulation,
pubmed-meshheading:10760564-Genes, Fungal,
pubmed-meshheading:10760564-Molecular Sequence Data,
pubmed-meshheading:10760564-Plasmids,
pubmed-meshheading:10760564-Promoter Regions, Genetic
|
| pubmed:year |
2000
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| pubmed:articleTitle |
Promoter elements involved in the expression of the Aspergillus parasiticus aflatoxin biosynthesis pathway gene avnA.
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| pubmed:affiliation |
Southern Regional Research Center, United States Department of Agriculture, PO Box 19687, 1100 R.E. Lee Blvd., New Orleans, LA, USA. jcary@nola.srrc.usda.gov
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| pubmed:publicationType |
Journal Article
|