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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0018787,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0034783,
umls-concept:C0035820,
umls-concept:C0185117,
umls-concept:C0205421,
umls-concept:C0330390,
umls-concept:C0441889,
umls-concept:C0686907,
umls-concept:C1511545,
umls-concept:C1514559,
umls-concept:C2911684
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pubmed:issue |
14
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pubmed:dateCreated |
2000-5-4
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|
pubmed:abstractText |
Transgenic cardiac beta(2)-adrenergic receptor (AR) overexpression has resulted in enhanced signaling and cardiac function in mice, whereas relatively low levels of transgenically expressed G(alphas) or beta(1)AR have resulted in phenotypes of ventricular failure. Potential relationships between the levels of betaAR overexpression and biochemical, molecular, and physiological consequences have not been reported.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1707-14
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10758054-Animals,
pubmed-meshheading:10758054-Calcium Channels,
pubmed-meshheading:10758054-Cardiac Output, Low,
pubmed-meshheading:10758054-Cardiomyopathies,
pubmed-meshheading:10758054-Cardiomyopathy, Dilated,
pubmed-meshheading:10758054-Echocardiography,
pubmed-meshheading:10758054-Electric Conductivity,
pubmed-meshheading:10758054-Fibrosis,
pubmed-meshheading:10758054-Hemodynamics,
pubmed-meshheading:10758054-Humans,
pubmed-meshheading:10758054-Mice,
pubmed-meshheading:10758054-Mice, Transgenic,
pubmed-meshheading:10758054-Myocardial Contraction,
pubmed-meshheading:10758054-Myocardium,
pubmed-meshheading:10758054-Osmolar Concentration,
pubmed-meshheading:10758054-Prospective Studies,
pubmed-meshheading:10758054-Receptors, Adrenergic, beta,
pubmed-meshheading:10758054-Time Factors
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pubmed:year |
2000
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pubmed:articleTitle |
Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level.
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pubmed:affiliation |
Department of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 45267-0590, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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