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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2000-5-4
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pubmed:abstractText |
Structural and functional alterations of the vasculature may contribute to complications of hypertension. Because angiotensin II may be pivotal in some of these vascular abnormalities, we tested the hypothesis that the angiotensin type 1 (AT(1)) receptor antagonist losartan, in contrast to the beta-blocker atenolol, would correct resistance artery abnormalities in patients with essential hypertension.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin Receptor Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Atenolol,
http://linkedlifedata.com/resource/pubmed/chemical/Losartan,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 2
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1653-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10758046-Acetylcholine,
pubmed-meshheading:10758046-Adult,
pubmed-meshheading:10758046-Angiotensin Receptor Antagonists,
pubmed-meshheading:10758046-Antihypertensive Agents,
pubmed-meshheading:10758046-Arteries,
pubmed-meshheading:10758046-Atenolol,
pubmed-meshheading:10758046-Buttocks,
pubmed-meshheading:10758046-Double-Blind Method,
pubmed-meshheading:10758046-Endothelium, Vascular,
pubmed-meshheading:10758046-Female,
pubmed-meshheading:10758046-Humans,
pubmed-meshheading:10758046-Hypertension,
pubmed-meshheading:10758046-Losartan,
pubmed-meshheading:10758046-Male,
pubmed-meshheading:10758046-Middle Aged,
pubmed-meshheading:10758046-Receptor, Angiotensin, Type 1,
pubmed-meshheading:10758046-Receptor, Angiotensin, Type 2,
pubmed-meshheading:10758046-Vascular Resistance,
pubmed-meshheading:10758046-Vasodilation
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pubmed:year |
2000
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pubmed:articleTitle |
Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan.
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pubmed:affiliation |
Medical Research Council Multidisciplinary Research Group on Hypertension, Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada. schiffe@ircm.qc.ca
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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