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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
2000-5-5
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pubmed:abstractText |
The effects of the conversion enzyme on the hydroelectrolytic balance in adult rats, maintained in standard lab conditions have been followed. The administration protocol for the conversion inhibitor (captopril) produced a blocking of the transformation of angiotensin I in angiotensin II only at the level of the cerebral structures, during the whole period of the treatment (40 micrograms/kg x 3/24 hours). Following the intracerebroventricular (ICV) administration of captopril, the fluid ingestion decreased diuresis and urinary elimination of Na+ and Ca++ increased. The results plead for the existence of a cerebral renin-angiotensin system, which intervenes in the control of the hydroelectrolyte metabolism.
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pubmed:language |
rum
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0048-7848
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
140-6
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pubmed:dateRevised |
2011-1-13
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pubmed:meshHeading |
pubmed-meshheading:10756941-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:10756941-Animals,
pubmed-meshheading:10756941-Captopril,
pubmed-meshheading:10756941-Catecholamines,
pubmed-meshheading:10756941-Diuresis,
pubmed-meshheading:10756941-Drinking,
pubmed-meshheading:10756941-Electrolytes,
pubmed-meshheading:10756941-Injections, Intraventricular,
pubmed-meshheading:10756941-Male,
pubmed-meshheading:10756941-Rats,
pubmed-meshheading:10756941-Rats, Wistar,
pubmed-meshheading:10756941-Time Factors,
pubmed-meshheading:10756941-Water
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pubmed:articleTitle |
[The effects of the intraventricular administration of captopril on water and ion metabolism in the rst].
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pubmed:affiliation |
Disciplina de Fiziologie, Facultatea de Medicin?, Universitatea de Medicin? ?i Farmacie Gr. T. Popa, Ia?i.
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pubmed:publicationType |
Journal Article,
English Abstract
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