Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-4-11
pubmed:abstractText
The transmission of Helicobacter pylori may occur by spread of organisms from gastric juice which has been introduced into the mouth by gastro-oesophageal reflux. The aim of this study was to quantify the load of H. pylori present in gastric juice available for transmission. Gastric antral biopsy and gastric juice samples were collected from 108 adult dyspeptic patients undergoing routine upper gastroscopy and the presence of H. pylori was determined. In all, 54 (50%) of 108 patients gave positive results in the gastric antral biopsy rapid urease test and for H. pylori histology. The gastric juice of 40 (37%) of patients gave positive results for the urease A gene by PCR assay; 34 (31%) of patients were positive by these three tests and H. pylori was cultured from the gastric juice of 13 (38%) of these patients. The median count of H. pylori in gastric juice was 1.75 x 10(1) cfu/ml. Viable organisms in gastric juice may lead to transmission of H. pylori when refluxed or vomited into the mouth.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-2615
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:10755628-Adolescent, pubmed-meshheading:10755628-Adult, pubmed-meshheading:10755628-Aged, pubmed-meshheading:10755628-Biopsy, pubmed-meshheading:10755628-Colony Count, Microbial, pubmed-meshheading:10755628-DNA, Bacterial, pubmed-meshheading:10755628-Dyspepsia, pubmed-meshheading:10755628-Female, pubmed-meshheading:10755628-Gastric Juice, pubmed-meshheading:10755628-Gastric Mucosa, pubmed-meshheading:10755628-Gastritis, pubmed-meshheading:10755628-Gastroscopy, pubmed-meshheading:10755628-Helicobacter Infections, pubmed-meshheading:10755628-Helicobacter pylori, pubmed-meshheading:10755628-Humans, pubmed-meshheading:10755628-Hydrogen-Ion Concentration, pubmed-meshheading:10755628-Male, pubmed-meshheading:10755628-Middle Aged, pubmed-meshheading:10755628-Polymerase Chain Reaction
pubmed:year
2000
pubmed:articleTitle
Quantitative culture of Helicobacter pylori from gastric juice: the potential for transmission.
pubmed:affiliation
Department of Oral Microbiology, St Bartholomew's and the Royal London School of Medicine and Dentistry. k.a.young@mds.qmw.ac.uk
pubmed:publicationType
Journal Article