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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2000-4-19
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pubmed:abstractText |
CTLA4IgG that binds to B7 effectively inhibits the signaling of CD28/B7 pathway and induces antigen-specific T-cell unresponsiveness in vitro and in vivo. We examined whether the development of obliterative bronchiolitis in a murine heterotopic airway transplantation model is T cell dependent and whether CTLA4IgG abrogates the development of obliterative bronchiolitis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD28,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA-4 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Ctla4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoconjugates,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/abatacept
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
743-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10755520-Animals,
pubmed-meshheading:10755520-Antigens, CD,
pubmed-meshheading:10755520-Antigens, CD28,
pubmed-meshheading:10755520-Antigens, CD80,
pubmed-meshheading:10755520-Antigens, Differentiation,
pubmed-meshheading:10755520-Bronchiolitis Obliterans,
pubmed-meshheading:10755520-CTLA-4 Antigen,
pubmed-meshheading:10755520-Humans,
pubmed-meshheading:10755520-Immune Tolerance,
pubmed-meshheading:10755520-Immunoconjugates,
pubmed-meshheading:10755520-Immunoglobulin G,
pubmed-meshheading:10755520-Kinetics,
pubmed-meshheading:10755520-Male,
pubmed-meshheading:10755520-Mice,
pubmed-meshheading:10755520-Mice, Inbred Strains,
pubmed-meshheading:10755520-Postoperative Complications,
pubmed-meshheading:10755520-T-Lymphocytes,
pubmed-meshheading:10755520-Trachea,
pubmed-meshheading:10755520-Transplantation, Heterotopic
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pubmed:year |
2000
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pubmed:articleTitle |
Blocking the CD28-B7 T-cell costimulatory pathway abrogates the development of obliterative bronchiolitis in a murine heterotopic airway model.
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pubmed:affiliation |
Section of Immunopathogenesis, Institute of Immunological Science, Hokkaido University, Sapporo, Japan.
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pubmed:publicationType |
Journal Article
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