Source:http://linkedlifedata.com/resource/pubmed/id/10751235
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2000-8-11
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| pubmed:abstractText |
We studied 70 Hong Kong Chinese patients with untreated hypertension and 47 normotensive controls. Blood pressure measurements and 24-h urine collection were performed for each patient, and were repeated 12 weeks later in 14 hypertensive patients who remained untreated. Twenty-two hypertensive patients underwent ambulatory blood pressure monitoring. The primary hypothesis tested was a correlation between diastolic blood pressure and 24-h urinary sodium excretion. In the hypertensive patients, diastolic blood pressure correlated with 24-h urinary sodium excretion (r=0.41, p<0.001), even after adjustment for age, gender, body mass index, ethanol intake and season (r=0.34, p=0.02). In normotensive controls, diastolic blood pressure did not correlate with sodium excretion (r=0.21, p=0.16). A correlation between diastolic blood pressure and sodium excretion was also observed in the patients who underwent ambulatory blood pressure monitoring (r=0.47, p=0.026), and in repeat measurements in untreated patients (r=0.60, p=0.02). Systolic blood pressure did not correlate with sodium excretion, although it increased with patient age (0.6+/-0.1 mmHg/year, p<0.001). In a multiple regression analysis with diastolic blood pressure as the dependent variable, the regression coefficient was 0.06+/-0.02 mmHg/mmol Na. The regression coefficients for ambulatory diastolic blood pressure and diastolic pressure repeated at 12 weeks were 0.07+/-0.03 and 0. 09+/-0.04 mmHg/mmol Na, respectively. Urinary sodium excretion was related to diastolic blood pressure in our hypertensive patients, accounting for 17% of the variance of diastolic blood pressure.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Mar
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| pubmed:issn |
1460-2725
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
93
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
163-8
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10751235-Adolescent,
pubmed-meshheading:10751235-Adult,
pubmed-meshheading:10751235-Age Factors,
pubmed-meshheading:10751235-Aged,
pubmed-meshheading:10751235-Alcohol Drinking,
pubmed-meshheading:10751235-Blood Pressure,
pubmed-meshheading:10751235-Body Mass Index,
pubmed-meshheading:10751235-Case-Control Studies,
pubmed-meshheading:10751235-China,
pubmed-meshheading:10751235-Creatinine,
pubmed-meshheading:10751235-Female,
pubmed-meshheading:10751235-Hong Kong,
pubmed-meshheading:10751235-Humans,
pubmed-meshheading:10751235-Hypertension,
pubmed-meshheading:10751235-Male,
pubmed-meshheading:10751235-Middle Aged,
pubmed-meshheading:10751235-Potassium,
pubmed-meshheading:10751235-Prospective Studies,
pubmed-meshheading:10751235-Regression Analysis,
pubmed-meshheading:10751235-Sex Factors,
pubmed-meshheading:10751235-Sodium,
pubmed-meshheading:10751235-Sodium Chloride, Dietary
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| pubmed:year |
2000
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| pubmed:articleTitle |
Diastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patients.
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| pubmed:affiliation |
Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong. mycheung@hkucc.khu.hk
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| pubmed:publicationType |
Journal Article
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