Linked Life Data

10750356

Source:http://linkedlifedata.com/resource/pubmed/id/10750356

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-5-17
pubmed:abstractText
Regional Cerebral blood flow (rCBF) and metabolism in major depression have been studied intently. Those studies are expected to reveal the mechanisms of the mood disorders, and also to give us valuable informations that the specific brain regions participating mood regulation. However, the data still have been inconsistent. In the present study we measured rCBF in patients with major depression and depressive state using xenon-CT CBF method. There is a tendencies that the rCBF values of normal control is the highest, and those of major depression is the lowest in most of the regions. The rCBF values in the patients with major depression are significantly lower than those in normal control in the right anterior frontal cortex, temporal cortex, putamen and thalamus. We also measured rCBF before and 90 minutes after giving calcium antagonist nilvadipine (4 mg, p.o.) in those subject. There is a tendency that nilvadipine increased in rCBF in normal control, however, it decreased in rCBF in major depression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-9717
pubmed:author
pubmed:issnType
Print
pubmed:volume
49 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
A112-3
pubmed:dateRevised
2008-8-7
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Regional cerebral blood flow in the patients with depressive disorders.
pubmed:affiliation
Dep. of Psychiatry, Showa University, Fujigaoka Hospital.
pubmed:publicationType
Journal Article